SkinCeuticals AGE Interrupter

Correct Severe Signs of Aging

One main cause of visible aging is glycation, which occurs when excess glucose molecules bind to collagen and elastin fibers and prompt the formation of advanced glycation end-products (A.G.E.s) that lead to severe skin wrinkling. Skinceuticals AGE Interrupter is a unique treatment formulated with 4% blueberry extract, 30% Proxylane™ and 0.2% phytosphingosine to help prevent the glycation process and correct severe signs of aging in mature skin.

Blueberry extract slows down the process of advanced glycation end-product (A.G.E.) formation, preventing collagen and elastin fibers from becoming rigid. Proxylane™ stimulates GAG synthesis, restoring water and nutrients to the dermal-epidermal junction. Phytosphingosine helps protect the skin’s barrier to alleviate discomfort associated with dry, aging skin.

In a clinical study using fluorescence measurements, blueberry extract in the presence of ribose as a reducing sugar had a similar dose response to positive control aminoguanidine, a potent glycation inhibitor. In addition, in reconstructed skin containing collagen modified by glycation, treatment with blueberry extract diminished CML antibodies (one of the A.G.E.s found in chronologically aged skin in-vivo), and returned previously over-expressed biomarkers to a normal pattern of distribution. These results indicate a return to skin’s normal morphological structure.

Massage a thin, even veil into the entire face, neck and chest once or twice daily.